15 papers across a decade of brain research

Precision targeting of C3+ reactive astrocyte subpopulations with endogenous ADAR in an iPSC-derived model

bioRxiv First author · Hyosung Kim, A Kjar, RJ Embalabala, JM Brunger, ES Lippmann 1 citation

Preprint — current line of work on RNA-editing sensors for neuroinflammation.

IQGAP2 regulates blood-brain barrier immune dynamics

iScience · KA Katdare et al. 8 citations

Induced neural progenitor specification from human pluripotent stem cells by a refined synthetic Notch platform

ACS Synthetic Biology · CA Hamann et al. 4 citations

Biofunctionalized gelatin hydrogels support development and maturation of iPSC-derived cortical organoids

Cell Reports · A Kjar et al. 39 citations

An arrayed CRISPR knockout screen identifies genetic regulators of GLUT1 expression

Scientific Reports · Y Shi et al. 6 citations

Reactive astrocytes transduce inflammation in a blood-brain barrier model through a TNF-STAT3 signaling axis

Nature Communications First author · Hyosung Kim, K Leng, J Park, AG Sorets, S Kim, A Shostak et al. 260 citations

CRISPRi screens in human iPSC-derived astrocytes elucidate regulators of distinct inflammatory reactive states

Nature Neuroscience · K Leng, IVL Rose, Hyosung Kim, W Xia, W Romero-Fernandez, B Rooney et al. 178 citations

Influence of Substrate Stiffness on Barrier Function in an iPSC-Derived In Vitro Blood-Brain Barrier Model

Cellular and Molecular Bioengineering · AM Bosworth et al. 28 citations

Nuclear receptor ligand screening in an iPSC-derived blood–brain barrier model identifies new contributors to leptin transport

Fluids and Barriers of the CNS · Y Shi et al. 15 citations

Rapid prototyping of cell culture microdevices using parylene-coated 3D prints

Lab on a Chip · BJ O'Grady et al. 54 citations

Generation of human pluripotent stem cell-derived fused organoids with oligodendroglia and myelin

STAR Protocols First author · Hyosung Kim, P Jiang 11 citations

OLIG2 drives abnormal neurodevelopmental phenotypes in human iPSC-based organoid and chimeric mouse models of Down syndrome

Cell Stem Cell · R Xu et al. 218 citations

Pluripotent stem cell-derived cerebral organoids reveal human oligodendrogenesis with dorsal and ventral origins

Stem Cell Reports First author · Hyosung Kim, R Xu, R Padmashri, A Dunaevsky, Y Liu, CF Dreyfus, P Jiang 157 citations

Nectin-like 4 complexes with choline transporter-like protein-1 and regulates Schwann cell choline homeostasis

Journal of Biological Chemistry · C Heffernan et al. 23 citations

Cadm3 (Necl-1) interferes with PI3 kinase/Akt signaling and inhibits Schwann cell myelination in vitro

Glia · MS Chen, Hyosung Kim, L Jagot-Lacoussiere, P Maurel 27 citations